Weight Loss
Tirzepatide
Also known as: GLP2-T, Mounjaro, Zepbound
Research use only. This protocol is compiled from published research literature and community documentation. It is for educational reference only and does not constitute medical advice.
Start Dose
2.5mg weekly SubQ
Begin here. Titrate conservatively based on response.
Standard Range
2.5mg → 15mg weekly. Titration: Weeks 1-4: 2.5mg. Weeks 5-8: 5mg. Weeks 9-12: 7.5mg. Weeks 13-16: 10mg. Weeks 17-20: 12.5mg. Weeks 21+: 15mg.
Titration Path
Start 2.5mg, titrate +2.5mg/4wk, max 15mg
Cycle
24
Weeks On
0
Weeks Off
Continuous use acceptable.
Routes
subcutaneous
Titration schedule: Weeks 1-4: 2.5mg. Weeks 5-8: 5mg. Weeks 9-12: 7.5mg. Weeks 13-16: 10mg. Weeks 17-20: 12.5mg. Weeks 21+: 15mg.
Notes
Dual incretin agonist (GLP-1, GIP). FDA-approved as Mounjaro/Zepbound. ~18% average weight loss.