Weight Loss
Semaglutide
Also known as: GLP1-S, Ozempic, Wegovy
Research use only. This protocol is compiled from published research literature and community documentation. It is for educational reference only and does not constitute medical advice.
Start Dose
0.25mg weekly SubQ
Begin here. Titrate conservatively based on response.
Standard Range
0.25mg → 2.4mg weekly. Titration: Weeks 1-4: 0.25mg. Weeks 5-8: 0.5mg. Weeks 9-12: 1mg. Weeks 13-16: 1.7mg. Weeks 17+: 2.4mg.
Titration Path
Start 0.25mg, titrate +0.25mg/4wk, max 2.4mg
Cycle
24
Weeks On
0
Weeks Off
Continuous use acceptable.
Routes
subcutaneous
Titration schedule: Weeks 1-4: 0.25mg. Weeks 5-8: 0.5mg. Weeks 9-12: 1mg. Weeks 13-16: 1.7mg. Weeks 17+: 2.4mg.
Notes
GLP-1 receptor agonist. FDA-approved for T2D (Ozempic) and weight management (Wegovy). ~14% average weight loss.